GJIIM.010106

Research Article

Clostridium perfringens liver abscess after transarterial chemoembolization for liver metastatic cancer

Xiaowei Liu1, Lingyan Chen1, Fulong Tang1 Tieyong Wang1, Linzhong Zhu2

1 Department of Oncology, Zhuolu County Hospital, 57 Nanguan street, Zhuolu County, Zhangjiakou, Hebei, 075600, China; 2 Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Interventional Therapy, Peking University Cancer Hospital & Institute, 52 Fucheng Road, Haidian District, Beijing, 100142, China

Correspondence
Linzhong Zhu, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Interventional Therapy, Peking University Cancer Hospital & Institute, 52 Fucheng Road, Haidian District, Beijing, 100142, China. E-mail: [email protected] 
Received: April 27, 2019; Accepted: November 8, 2019; Published online: December 23, 2019. 
Cite this paper: Liu, X. Chen, L., Tang, F., Wang, T. and Zhu, L. (2020) Clostridium perfringens liver abscess after transarterial chemoembolization for liver metastatic cancer. Global Journal of Imaging and Interventional Medicine, 1(1):26-33. https://naturescholars.com/gjiim.010106. https://doi.org/10.46633/gjiim.010106. 
Copyright © 2020 by Scholars Publishing, LLC. 

Abstract

Transarterial chemoembolization (TACE) can cause severe complication including liver abscess. Most liver abscess are caused by E. coli. However, in our center, Clostridium perfringens were identified as a new pathogen in 3 cases, where CT scan showed gas-forming cavity located in the liver. The patients showed obvious symptoms of poisoning, shock, and multiple organ failure. 1 case died soon, and 2 cases survived. The pathogenic understanding, early diagnosis and corresponding treatment of this disease are important to ensure the survival of patients.

Key words: Chemoembolization, Liver cancer; Liver Abscess, Clostridium perfringens