Xia-Min Cheng, PhD
Associate Professor
Principal Investigator
Nanjing Technlogy University
Nanjing, China

Biography                 

1998-2002, BSc, Department of Chemistry, Nankai University, China

2002-2005, MSc, State key Laboratory of Elemento-organic Chemistry, The Research Institute of Elemento-organic Chemistry, Nankai University, China

2006-2009, MSc, Division of Chemistry and Biological Chemistry, Nanyang Technological University, Singapore

2009-2014, PhD, Department of Chemistry, National University of Singapore, Singapore

2015-2017, Research Fellow, National University of Singapore, Singapore

2017-present, Associate Professor, Nanjng Technology University, China

        Research Interests         

1. Kinase inhibitor for targeted cancer therapy;

2. Fluorescent probe for cancer cell imaging and therapy;

3. Fabrication of nanomaterials for drug delivery.

        Selected Publications               

1.      Cai，X.; Mao, D.; Wang,C.; Kong, D.; Cheng, X.;* and Liu, B.* (* Corresponding author). Multifunctional Liposome: Bright AIEgen-Lipid Conjugate with Strong Photosensitization, Angew. Chem. Int. Ed. (2018), 57, 16396 –16400.

2.      Cheng, X.;# Zhang, R.;# Cai, X.; and Liu, B.* (# equal contribution). A Reusable and Naked-eye Molecular Probe with Aggregation-induced Emission (AIE) Characteristics for Hydrazine Detection. J. Mater. Chem. B, (2017), 5，3565-3571.

3.      Yuan, Y.; Xu, S.; Cheng, X.; and Liu, B.* Bioorthogonal Turn-On Probe Based on Aggregation-Induced Emission Characteristics for Cancer Cell Imaging and Ablation. Angew. Chem. Int. Ed., (2016), 55, 6457–6461.

4.      Yuan, Y.;# Zhang, R.;# Cheng, X.;# Xu, S.; and Liu, B.* (# equal contribution). A FRET Probe with AIEgen as the Energy Quencher: Dual Signal Turn-on for Self-validated Caspase Detection.Chem. Sci., (2016), 7, 4245-4250.

5.      Cheng, X.; Li, L.; Uttamchandani, M.; Yao, S. Q.* A Tuned Affinity-Based Staurosporine Probe for In Situ Profiling of Protein Kinases. Chem. Commun., (2014), 50, 2851-2853.

6.      Cheng, X.; Li, L.; Uttamchandani, M.; Yao, S. Q.* In Situ Proteome Profiling of C75, a Covalent Bioactive Compound with Potential Anti-cancer Activities. Org. Lett., (2014), 16, 1414-1417.