Zhaofeng Huang, PhD Associate Professor Institute of Human Virology Zhongshan School of Medicine Sun Yat-sen University
Education:
2000-2003 Ph.D., Genetics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
1997-2000 M.S., Genetics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Work experience:
March 2010-present: Sun Yat-sen University, Zhongshan School of Medicine, Institute of Human Virology
Jan. 2009-Feb. 2010: Jean Mayer USDA Human Nutrition Research Center at Aging at Tufts University (HNRCA), Nutrition Immunology Laboratory. Research Associate
May 2004 – Dec. 2008: University of Illinois at Chicago, Department of Microbiology & Immunology. Postdoctoral Research Associate
Selected publication:
- Xu X, Yu B, Cai W, Zhaofeng Huang. TCF1 deficiency ameliorates autoimmune lymphoproliferative syndrome (ALPS)-like phenotypes of lpr/lpr mice. Scand J Immunol. 2017 Mar 28. doi: 10.1111/sji.12546.
- Zhao M, Huanpeng Chen, Ding Q, Xu X, Yu B, Zhaofeng Huang. Nuclear Factor Erythroid 2-related Factor 2 Deficiency Exacerbates Lupus Nephritis in B6/lpr mice by Regulating Th17 Cell Function. Sci Rep. 2016 Dec 12;6:38619. doi: 10.1038/srep38619
- Qingfeng Ding, Mei Zhao, Bolan Yu, Chuan Bai, Zhaofeng Huang. Identification of tetraazacyclic compounds as novel potent inhibitors antagonizing RORγt activity and suppressing Th17 cell differentiation. Plos One 2015 , 10(9):e0137711 DOI: 10.1371/journal.pone.0137711
- Qingfeng Ding, Mei Zhao, Chuan Bai, Bolan Yu, Zhaofeng Huang. Inhibition of RORγt activity and Th17 differentiation by a set of novel compounds. BMC immunology 2015, 16:32. DOI: 10.1186/s12865-015-0097-9
- Huang Z, Wang R, Xie H, Shang W, Manicassamy S and Sun Z. Stabilized β-catenin potentiates peripheral T cell apoptosis by up-regulating Fas. Journal of Immunology 2008; 180: 6586- 6592.
- Huang Z, Xie H, Wang R, and Sun Retinoid-related orphan receptor γt is a potential therapeutic target for controlling inflammatory autoimmunity. Expert Opinion on Therapeutic Targets 2007, 11(6):737-743
- Huang Z, Xie H, Ioannidis V, Held W, Clevers H, Sadim M, and Sun Transcriptional Regulation of CD4 Gene Expression by T Cell Factor-1/β-Catenin Pathway. Journal of Immunology 2006; 176: 4880–4887