Review

Advances in Research on Immune Mechanism of Prostate Cancer Based on Bioinformatics

Xiao-Wu Pi, Ying Xiong✉

Department of Urology, School of Medicine, The First Clinical Medical College, Yangtze University, Jingzhou, Hubei 434023, China

✉ Correspondence
Ying Xiong, Department of Urology, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei 434000, China. Email: [email protected]. Telephone number: 86-18163138805.

Received: November 13, 2020; Accepted: June 29, 2021; Published: September 11, 2021.
Cite this paper: Xiao-Wu Pi and Ying Xiong (2021) Advances in Research on Immune Mechanism of Prostate Cancer Based on Bioinformatics. Global Journal of Immunology, 2(1): 18-31. 
https://naturescholars.com/gji.020102. https://doi.org/10.46633/gji.020102
Copyright© 2021 by Scholars Publishing, LLC.

Abstract

The incidence of prostate cancer, one of the most common cancers in the male urogenital system, is increasing year by year. At present, the research on the immune mechanism of prostate cancer is not well discerned. In recent years, the application of bioinformatics in the study of the immune mechanism of prostate cancer has been rapidly developed, which has not only brought new modes for the research on the prostate cancer development and immune mechanisms, but also has been recognized as the current hot spot in tumor research. This paper reviews the related applications of bioinformatics in the study of the immune mechanism of prostate cancer and summarizes the development trend.

Key words: Bioinformatics; Immunotherapy; Programmed Death Protein 1 (PD-1); Prostate Cancer (PCa); Castration-Resistant Prostate Cancer (CRPC); miRNA; Tumor Markers.